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KMID : 0361820100290020105
Journal of the Korean Society of Medical Ultrasound
2010 Volume.29 No. 2 p.105 ~ p.113
Ultrasonographic Differentiation of Small Angiomyolipoma from Renal Cell Carcinoma by Measuring Relative Echogenicity on PACS
Lee Myoung-Seok

Cho Jeong-Yeon
Kim Seung-Hyup
Abstract
Purpose: To retrospectively evaluate the diagnostic value of ultrasonographic differentiation of small angiomyolipomas (AMLs) from renal cell carcinomas (RCCs) by measuring relative echogenicity (RE) on PACS.

Materials and Methods: Thirty-six cases of < 3 cm, pathologically-proven RCCs and 42 cases of size-matched AMLs were enrolled. We measured the grayscale representing echogenicity of the mass, the renal cortex, and the sinus fat on PACS using a ROI cursor. The RE of the tumor was calculated by setting the grayscale of the renal cortex and sinus fat as 0% and 100%, respectively. We compared REs of AMLs and RCCs, including subgroups of each tumor. ROC analyses between RCCs and AMLs or non-fatty AMLs were performed for obtaining diagnostic performance (Az value) of RE measurement and for extracting sensitivities of RE with fixed specificities of 90% and 95%.

Results: The RE of AMLs was higher than RCCs (p < 0.05). The RE of non-fatty AMLs was significantly lower than fatty AMLs, and higher than any subgroups of RCCs (p < 0.05). RE measurement provided good diagnostic performance (Az ¡Ã 0.840, p < 0.05) with competitive sensitivity/specificity for differentiating AMLs from RCCs regardless of AML subgroups.

Conclusions: RE measurement on PACS can be helpful in the differential diagnosis of small AMLs and RCCs with the intrinsic merits of ultrasonography.
KEYWORD
Kidney, Angiomyolipoma, Renal cell carcinoma, PACS, Ultrasound
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